Cilmi-baarayaasha UCF waxay soo saareen jeermis-dile-ku-saleysan nanoparticle kaasoo si joogto ah u dili kara fayrasyada dusha sare ilaa 7 maalmood - daahfurka laga yaabo inuu noqdo hub xooggan oo ka dhan ah COVID-19 iyo fayrasyada kale ee cudur-sidaha ah ee soo baxaya.
Cilmi-baadhistan ayaa toddobaadkan lagu daabacay joornaalka ACS Nano oo ka tirsan Ururka Kiimikada Maraykanka oo ay sameeyeen koox khubaro badan oo fayras iyo injineero ah oo ka socda jaamacadda iyo madaxa shirkad tignoolajiyadeed oo ku taal Orlando.
Christina Drake, oo ah arday wax ka bartay Jaamacadda Bartamaha Florida sanadkii 2007 iyo aasaasihii Kismet Teknolojiyada, ayaa lagu dhiirigeliyay inay horumariso jeermiska dila ka dib safar ay ku tagtay dukaanka raashinka bilowga masiibada. Halkaa, waxay ku aragtay shaqaale ku buufinaya jeermiska jeermiska dilaha ee qaboojiyaha ka dibna isla markiiba iska tirtirtay buufintii.
"Markii hore fikradaydu waxay ahayd inaan soo saaro jeermis-dile degdeg ah," ayay tidhi, "laakin waxaan la hadalnay macaamiisha - sida dhakhaatiirta iyo dhakhaatiirta ilkaha - si aan u ogaano jeermiska ay runtii rabaan. Iyaga Waxa ugu muhiimsan waa waxa waara. Waxay sii wadi doontaa inay jeermiska ka saarto meelaha sare ee xidhiidhka sida gacan-qabashada albaabka iyo sagxadaha muddo dheer ka dib codsiga.
Drake wuxuu iskaashi la sameeyay Dr. Sudipta Seal, injineer agabka UCF iyo khabiir nanoscience ah, iyo Dr. Griff Parks, virologist, madaxa cilmi baarista ee Iskuulka Caafimaadka, iyo Hormuudka Dugsiga Burnett ee Sayniska Biomedical. Iyada oo ay maalgelinayaan Mu'asasada Sayniska Qaranka, Kismet Tech, iyo Waddada Farsamada Sare ee Florida, cilmi-baarayaashu waxay sameeyeen jeermis-dile nanoparticle ah oo la farsameeyay.
Maadkeeda firfircooni waa nanostructure la farsameeyey oo loo yaqaan cerium oxide, oo loo yaqaanno sifooyinka antioxidant-ka ee dib-u-soo-nooleynta. Nanoparticles Cerium oxide waxaa lagu beddelaa qadar yar oo lacag ah si ay uga dhigaan kuwo waxtar leh oo ka dhan ah cudurada.
"Waxay ka shaqeysaa labada kimistari iyo makaanikada," ayuu yiri Seal, oo baranaya nanotechnology in ka badan 20 sano. "Nanoparticles waxay sii daayaan electrons si ay u oksijiyeen fayraska oo ay uga dhigaan mid aan shaqaynayn. Farsamo ahaan, waxay sidoo kale isku dhejiyaan fayraska oo ay u dillaacaan dusha sare sida buufin wax qarxinaya."
Badi jeermis-dileyaasha tirtirayaasha ama buufisyada waxay jeermi doonaan dusha saddex ilaa lix daqiiqo gudahood ka dib isticmaalka, laakiin ma jirto wax saamayn ah oo hadhay. Tani waxay ka dhigan tahay in dusha sare loo baahan yahay in si isdaba joog ah loo tirtiro si loo nadiifiyo si looga fogaado infekshinka fayraska badan sida COVID-19. Samaynta nanoparticle waxa ay ilaalisaa awoodda ay u leedahay in ay firfircooni geliso noolaha oo sii wadaa in ay jeermiso dusha sare ilaa 7 maalmood ka dib hal codsi.
"Dabaysha jeermiska disha ayaa muujisa waxqabad fayruska lidka ku ah oo ka dhan ah todobo fayras oo kala duwan," Parks ayaa sharraxay, shaybaarkiisuna wuxuu mas'uul ka yahay tijaabinta caabbinta caanaha ee fayraska "qaamuuska". "Kaliya ma muujin guryaha ka-hortagga fayraska ee ka dhanka ah coronaviruses iyo rhinoviruses, laakiin sidoo kale waxay caddeeyeen inay wax ku ool u yihiin fayrasyada kale ee kala duwan ee leh qaabab kala duwan iyo kakan. Waxaan rajaynaynaa in awooddan cajiibka ah ee lagu dilo, jeermis-dilahan uu sidoo kale noqon doono qalab aad waxtar u leh oo looga hortagayo fayrasyada kale ee soo baxaya."
Saynis yahanadu waxay aaminsan yihiin in xalkani uu saameyn weyn ku yeelan doono deegaanka daryeelka caafimaadka, gaar ahaan hoos u dhigida dhacdooyinka caabuqyada isbitaallada-sida Staphylococcus aureus u adkaysta methicillin (MRSA), Pseudomonas aeruginosa iyo Clostridium difficile -Infekshannadani waxay saameeyaan in ka badan saddex-meelood meel. Bukaannada la dhigay isbitaallada Mareykanka.
Si ka duwan jeermis-dileyaal badan oo ganacsi, caanahan kuma jiraan kiimikooyin waxyeello leh, taas oo muujinaysa in ay ammaan tahay in la isticmaalo oog kasta. Marka loo eego shuruudaha Hay'adda Ilaalinta Deegaanka ee Mareykanka, baaritaanada sharciyeynta ee maqaarka iyo cuncunka unugyada isha ma muujin wax saameyn ah oo waxyeelo leh.
"In badan oo ka mid ah jeermiska-jeermiska guriga ee hadda la heli karo waxaa ku jira kiimikooyin waxyeello u leh jirka ka dib soo-gaadhista soo noqnoqda," Drake ayaa yidhi. "Alaabadayada nanoparticle-ku salaysan waxay yeelan doonaan badbaado heer sare ah, taas oo door muhiim ah ka ciyaari doonta yaraynta guud ahaan soo-gaadhista bini'aadamka ee kiimikooyinka."
Cilmi-baaris dheeraad ah ayaa loo baahan yahay ka hor intaanay alaabtu soo gelin suuqa, taas oo ah sababta wejiga xiga ee cilmi-baaristu ay diiradda saari doonto waxqabadka jeermiska-jeermiska ee codsiyada la taaban karo ee ka baxsan shaybaarka. Shaqadani waxay baran doontaa sida jeermiska jeermiska dila ay u saameeyaan arrimaha dibadda sida heerkulka ama iftiinka qorraxda. Kooxdu waxay wadahadalo kula jirtaa shabakadda cisbitaalka maxalliga ah si ay ugu tijaabiso alaabta xarumahooda.
Drake wuxuu raaciyay: "Waxaan sidoo kale sahamineynaa horumarinta filim semi-joogta ah si aan u aragno inaan dabooli karno oo aan dabooli karno sagxadaha isbitaallada ama gacmaha albaabada, meelaha u baahan in jeermiska laga saaro, ama xitaa meelaha si firfircoon oo joogto ah ula xiriira."
Seal waxa uu ku biiray Waaxda Qalabka Sayniska iyo Injineerinka ee UCF sanadkii 1997, taas oo qayb ka ah UCF School of Engineering iyo Computer Science. Wuxuu ka shaqeeyaa dugsiga caafimaadka wuxuuna xubin ka yahay kooxda prosthetic UCF Bioonix. Isagu waa agaasimihii hore ee Xarunta Sayniska iyo Tignoolajiyada ee UCF Nano iyo Xarunta Habaynta iyo Falanqaynta Qalabka Sare. Waxa uu shahaadada PhD ka qaatay injineerinka agabka ee Jaamacadda Wisconsin, isaga oo aan ka yarayn cilmiga biochemistry, waana cilmi-baare postdoctoral ah oo ka tirsan Shaybaadhka Qaranka ee Lawrence Berkeley ee Jaamacadda California, Berkeley.
Ka dib markii uu ka shaqeeyay Wake Forest School of Medicine muddo 20 sano ah, Parks wuxuu yimid UCF 2014, halkaas oo uu u soo shaqeeyay borofisar iyo madaxa Waaxda Microbiology iyo Immunology. Wuxuu qaatay shahaadada Ph.D. ee biochemistry ee Jaamacadda Wisconsin waana cilmi-baare ka tirsan Ururka Kansarka Mareykanka ee Jaamacadda Waqooyi-galbeed.
Cilmi-baarista waxaa iska kaashaday Candace Fox, oo ah cilmi-baare postdoctoral ah oo ka socda UCF School of Medicine, Craig Neal oo ka socda UCF School of Engineering iyo Computer Science, iyo ardayda ka qalin jabisay Tamil Sakthivel, Udit Kumar, iyo Yifei Fu oo ka socda UCF School of Engineering iyo Computer Science .
Sida wax kasta oo aad ka akhrido internetka, maqaalkan waa in aan loo tixgelin talobixin caafimaad; fadlan la tasho dhakhtarkaaga ama bixiyaha daryeelka aasaasiga ah ka hor inta aanad wax isbeddel ah ku samayn nidaamkaaga caafimaad.
Waligaa noolow! Waxaa wada marti galiyay Dr. Ron Klatz iyo la-martigeliyayaasha Carol Petersen, RPh, CNP iyo martida gaarka ah Dr. Daved Rosensweet
Dhimasho la'aanta Hadda oo leh Dr. Ron Klatz, la-shaqeeyaha Carol Petersen RPh, CNP iyo martida gaarka ah Dr. Frank Shallenberger
Dhimasho la'aanta Hadda oo leh Dr. Ron Klatz, la-shaqeeyaha Carol Petersen RPh, CNP iyo martida gaarka ah Dr. Jin Xiongshe
Waqtiga boostada: Sebtembar-07-2021