Alum UCF iyo dhowr cilmi-baarayaal ayaa isticmaalay nanotechnology si ay u horumariyaan wakiilkan nadiifinta, kaas oo iska caabin kara todobo fayras ilaa 7 maalmood.
Cilmi-baarayaasha UCF waxay soo saareen jeermis-dile-ku-saleysan nanoparticle kaasoo si joogto ah u dili kara fayrasyada dusha sare ilaa 7 maalmood - daahfurkaani wuxuu noqon karaa hub xooggan oo ka dhan ah COVID-19 iyo fayrasyada kale ee cudur-sidaha ah ee soo baxaya.
Cilmi-baadhistan ayaa toddobaadkan lagu daabacay joornaalka ACS Nano oo ka tirsan Ururka Kiimikada Maraykanka oo ay sameeyeen koox khubaro badan oo fayras iyo injineero ah oo ka socda jaamacadda iyo madaxa shirkad tignoolajiyadeed oo ku taal Orlando.
Christina Drake '07PhD, aasaasaha Kismet Technologies, waxaa dhiirigeliyay safar ay ku tagtay dukaanka raashinka bilawgii masiibada waxayna soo saartay jeermis-dileyaal. Halkaa, waxay ku aragtay shaqaale ku buufinaya jeermiska jeermiska dilaha ee qaboojiyaha ka dibna isla markiiba iska tirtirtay buufintii.
"Markii hore fikradaydu waxay ahayd inaan soo saaro jeermis-dile degdeg ah," ayay tidhi, "laakin waxaan la hadalnay macaamiisha sida dhakhaatiirta iyo dhakhaatiirta ilkaha si aan u fahanno jeermiska ay runtii rabaan. Waxa ugu muhiimsan iyaga waa shay sii raagaya, waxay sii wadi doontaa inay jeermiska ka saarto meelaha sare ee xidhiidhka sida gacanka albaabka iyo sagxada muddo dheer ka dib codsiga. "
Drake wuxuu la shaqeeyaa Sudipta Seal, injineer agabka UCF ah iyo khabiir nanoscience ah, iyo Griff Parks, virologist, madaxa cilmi baarista ee Dugsiga Daawada, iyo hormuudka Dugsiga Burnett ee Sayniska Biomedical. Iyada oo ay maalgelinayaan Mu'asasada Sayniska Qaranka, Kismet Tech, iyo Waddada Farsamada Sare ee Florida, cilmi-baarayaashu waxay sameeyeen jeermis-dile nanoparticle ah oo la farsameeyay.
Maadkeeda firfircooni waa nanostructure la farsameeyey oo loo yaqaan cerium oxide, oo loo yaqaanno sifooyinka antioxidant-ka ee dib-u-soo-nooleynta. Nanoparticles Cerium oxide waxaa lagu beddelaa qadar yar oo lacag ah si ay uga dhigaan kuwo waxtar leh oo ka dhan ah cudurada.
"Waxay ka shaqeysaa labada kimistari iyo mishiinada," ayuu yiri Seal, oo baranaya nanotechnology in ka badan 20 sano. "Nanoparticles waxay sii daayaan electrons si ay u oksijiyeen fayraska oo ay uga dhigaan mid aan shaqaynayn. Farsamo ahaan, waxay sidoo kale isku dhejiyaan fayraska oo ay dillaacaan dusha sare, sida inay dilaan buufin."
Badi jeermis-dileyaasha tirtirayaasha ama buufisyada waxay jeermi doonaan dusha saddex ilaa lix daqiiqo gudahood ka dib isticmaalka, laakiin ma jirto wax saamayn ah oo hadhay. Tani waxay ka dhigan tahay in dusha sare loo baahan yahay in si isdaba joog ah loo tirtiro si loo nadiifiyo si looga fogaado infekshinka fayraska badan sida COVID-19. Samaynta nanoparticle waxa ay ilaalisaa awoodda ay u leedahay in ay firfircooni geliso noolaha oo sii wadaa in ay jeermiso dusha sare ilaa 7 maalmood ka dib hal codsi.
"Dawada jeermis-dileyaasha waxay muujinaysaa hawl-qabad weyn oo ka-hortagga fayraska oo ka dhan ah toddoba fayras oo kala duwan," ayuu yidhi Parks, oo shaybaadhkoodu uu mas'uul ka yahay tijaabinta caabbinta caanaha ee fayraska "qaamuuska". "Ma aha oo kaliya inay muujiso sifooyinka fayraska ka hortagga coronaviruses iyo rhinoviruses, laakiin waxay sidoo kale caddaynaysaa inay waxtar u leedahay fayrasyo kale oo kala duwan oo leh qaabab kala duwan iyo isku dhafan. Waxaan rajaynaynaa in awooddan cajiibka ah ee lagu dilo, jeermis-dileyaashani sidoo kale waxay noqon doontaa qalab wax ku ool ah oo ka dhan ah fayrasyada kale ee soo baxaya."
Saynis yahanadu waxay aaminsan yihiin in xalkani uu saameyn weyn ku yeelan doono deegaanka daryeelka caafimaadka, gaar ahaan hoos u dhigida dhacdooyinka caabuqa isbitaalku keeno, sida Staphylococcus aureus u adkaysta methicillin (MRSA), Pseudomonas aeruginosa iyo Clostridium difficile—- Waxay saameeyaan in ka badan hal 30kiiba. Bukaannada la dhigay isbitaallada Mareykanka.
Si ka duwan jeermis-dileyaal badan oo ganacsi, caanahan kuma jiraan kiimikooyin waxyeello leh, taas oo muujinaysa in ay ammaan tahay in la isticmaalo oog kasta. Marka loo eego shuruudaha Hay'adda Ilaalinta Deegaanka ee Mareykanka, baaritaanada sharciyeynta ee maqaarka iyo cuncunka unugyada isha ma muujin wax saameyn ah oo waxyeelo leh.
"In badan oo ka mid ah jeermiska-jeermiska guriga ee hadda la heli karo waxaa ku jira kiimikooyin waxyeello u leh jirka ka dib soo-gaadhista soo noqnoqda," Drake ayaa yidhi. "Alaabadayada nanoparticle-ku salaysan waxay yeelan doonaan badbaado heer sare ah, taas oo door muhiim ah ka ciyaari doonta yaraynta guud ahaan soo-gaadhista bini'aadamka ee kiimikooyinka."
Cilmi-baaris dheeraad ah ayaa loo baahan yahay ka hor intaanay alaabtu soo gelin suuqa, taas oo ah sababta wejiga xiga ee cilmi-baaristu ay diiradda saari doonto waxqabadka jeermiska-jeermiska ee codsiyada la taaban karo ee ka baxsan shaybaarka. Shaqadani waxay baran doontaa sida jeermiska jeermiska dila ay u saameeyaan arrimaha dibadda sida heerkulka ama iftiinka qorraxda. Kooxdu waxay wadahadalo kula jirtaa shabakadda cisbitaalka maxalliga ah si ay ugu tijaabiso alaabta xarumahooda.
"Waxaan sidoo kale raadineynaa horumarinta filim si joogto ah u ah si aan u aragno haddii aan dabooli karno oo aan dabooli karno sagxadaha isbitaallada ama albaabbada, meelaha u baahan in la jeermiyo, ama xitaa meelaha xiriir firfircoon oo joogto ah," Drake ayaa yiri.
Seal waxa uu ku biiray Waaxda Qalabka Sayniska iyo Injineerinka ee UCF sanadkii 1997, taas oo qayb ka ah UCF School of Engineering iyo Computer Science. Prosthesis. Isagu waa agaasimihii hore ee Xarunta Sayniska iyo Tignoolajiyada ee UCF Nano iyo Xarunta Habaynta iyo Falanqaynta Qalabka Sare. Waxa uu shahaadada PhD ka qaatay injineerinka agabka ee Jaamacadda Wisconsin, isaga oo aan ka yarayn cilmiga biochemistry, waana cilmi-baare postdoctoral ah oo ka tirsan Shaybaadhka Qaranka ee Lawrence Berkeley ee Jaamacadda California, Berkeley.
Ka dib markii uu ka shaqeeyay Wake Forest School of Medicine muddo 20 sano ah, Parkes wuxuu yimid UCF 2014, halkaas oo uu u soo shaqeeyay borofisar iyo madaxa Waaxda Microbiology iyo Immunology. Wuxuu qaatay shahaadada Ph.D. ee biochemistry ee Jaamacadda Wisconsin waana cilmi-baare ka tirsan Ururka Kansarka Mareykanka ee Jaamacadda Waqooyi-galbeed.
Daraasada waxaa iska kaashaday Candace Fox, oo ah cilmi-baare postdoctoral ee kuliyadda caafimaadka, iyo Craig Neal oo ka socday Iskuulka Injineerinka iyo Sayniska Kombiyuutarka. Tamil Sakthivel, Udit Kumar, iyo Yifei Fu, ardayda ka qalin jabisay Dugsiga Injineerinka iyo Sayniska Kombiyuutarka, sidoo kale waa wada-qoraalayaal.
Waqtiga boostada: Sebtembar-04-2021